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The mutation in Caucasian people of European heritage is
2019-11-11
The Δ32 mutation in Caucasian people of European heritage is quite common but extremely rare in Asian and African countries (Huang et al., 1996). We recently reported the presence of this mutation from India (Husain et al., 1998a) and established the complete inheritance pattern (Husain et al., 1998
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br Methods br Results Our study focused on consecutive postu
2019-11-11
Methods Results Our study focused on consecutive postural adjustments (CPAs) between IS and BS (the shaded areas on Fig. 2); that is to say, the Rx kinetics that occur after the end of an upper limb movement. It was dedicated to examining the main features of CPAs and the influence of movement
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To estimate the nonparametric regression we use a B
2019-11-11
To estimate the nonparametric regression, we use a B-spline basis. Let be the space of polynomial splines of degree and denote a normalized B-spline basis with and , where is the supremum norm. For any and , we have for some coefficients . Here we allow to increase with and differ for differ
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It is noteworthy that epidemiological studies
2019-11-11
It is noteworthy that epidemiological studies have demonstrated that some GAD patients have experienced anxiety symptoms in childhood and young adulthood, whereas others have developed their disorder at a later age (especially persons ≥ 50 years of age) (Hoehn-Saric et al., 1993; Le Roux et al., 200
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Introduction Human cytomegalovirus CMV is a herpesvirus whic
2019-11-11
Introduction Human cytomegalovirus (CMV) is a herpesvirus which has a ubiquitous and worldwide distribution, and is the most frequent cause of congenital infection (Kenneson and Cannon, 2007). The prevalence is around 0.5–1% of all live births and is the leading cause of sensorineural hearing loss
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Enolase is an example of a moonlighting protein that display
2019-11-11
Enolase is an example of a moonlighting protein that displays multiple biological actions, including plasminogen, laminin, fibronectin, mucin and cytokeratin binding properties. It has also been described as a complement-evasion protein and as a protein capable of inducing neutrophil trap formation.
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br EBV Infection Epstein Barr virus EBV human herpesvirus wa
2019-11-11
EBV Infection Epstein–Barr virus (EBV, human herpesvirus 4) was discovered 50 years ago, when Epstein, Achong, and Barr used electron microscopy to identify viral particles in Burkitt\'s lymphoma cells. It belongs to the lymphocryptovirus (LCV) genus of the gammaherpesvirus subfamily (Fig. 1A). T
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Upstream Stimulatory Factor USF binding to
2019-11-11
Upstream Stimulatory Factor (USF) binding to the −65 E-box is required for the regulation of FAS promoter activity in fasting/feeding [97], [98]. DNA-PK are identified as a USF-interacting protein [99]. In response to feeding/insulin, the transient double-stranded DNA breaks occurred during the tran
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br Competing interests br Acknowledgements br Introduction D
2019-11-11
Competing interests Acknowledgements Introduction Diacylglycerol kinase (DGK) phosphorylates diacylglycerol (DG) in biomembranes to produce phosphatidic glycine receptors (PA) [1], [2], [3], [4], [5], [6]. To date, ten mammalian DGK isozymes (α, β, γ, δ, ε, ζ, η, θ, ι and κ) have been iden
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br Cytokines as targets for the
2019-11-11
Cytokines as targets for the development of drugs Since the first scientific evidence describing the large number of cytokines and their functional roles and involvement in molecular mechanism of various diseases or disorders researchers have targeted cytokines. (Isaacs and Lindenmann, 1957), Des
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br Materials and methods br Results br
2019-11-11
Materials and methods Results Discussion The nitric oxide generating enzymes of the NOS family comprise three isoforms: nNOS, iNOS and eNOS [31]. Expression of eNOS is mainly found in endothelial Desformylflustrabromine hydrochloride where it physically promotes vasodilation [32]. Converse
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The quaternary structure of many
2019-11-11
The quaternary structure of many of the family B members (i.e., secretin, glucagon, glucagon-like peptide and sodium fluoride receptors) have been actively studied and it has been demonstrated that they can form homodimers/oligomers (Gao et al., 2009; Ng & Chow, 2015; Ng, Lee, & Chow, 2013). Harik
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Addressing whether impaired activation of D and
2019-11-08
Addressing whether impaired activation of D1 and D2 receptors regulates memory capacity is relevant for all human pathologies that lead to reduced activation of these luteolin pathways, such as ageing [39], certain genetic polymorphisms [40] and neurodegenerative disorders. In this study, we have t
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br Experimental Procedures DNA synthesis reagents were purch
2019-11-08
Experimental Procedures DNA synthesis reagents were purchased from Glen Research (Sterling, VA). A solution of 0.1 M triethylamine acetate (TEAA) (pH 6.5) was used as HPLC buffer A, and HPLC-grade acetonitrile from Oceanpak (Sweden) was used as HPLC buffer B. All other chemicals were obtained fro
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br Discussion Electroporation is a convenient and efficient
2019-11-08
Discussion Electroporation is a convenient and efficient way to introduce foreign material into polymyxin sulfate [10], [16], [17], [18]. There are a lot of different protocols for transfection with electroporation. It was reported that there are several parameters that are relevant to successfu
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